When you install an Axiom product for AutoCAD, it will detect the versions of AutoCAD you have installed and implement the file and folder structure necessary to load your Axiom software when AutoCAD is loaded. When a new version of AutoCAD is installed, it won't have the necessary Axiom folders and files in place to load the Axiom software.
Solution: Just reinstall your Axiom software and it will establish everything needed for Axiom software to load in your newly installed version of AutoCAD.

(Note: If a reinstallation of your Axiom software does not solve the issue, it could be either that you have an old installer or that you've installed a version of AutoCAD that we haven't yet added support for. Check with the Axiom delivery department LicenseActivation@AxiomInt.com to get the latest and to make sure we've added support for your new version of AutoCAD.)